Detalhe da pesquisa
1.
Target-controlled Infusion of Remimazolam in Healthy Volunteers Shows Some Acute Tolerance.
Anesthesiology
; 140(2): 207-219, 2024 Feb 01.
Artigo
Inglês
| MEDLINE | ID: mdl-37889844
2.
A population pharmacokinetic model of remimazolam for general anesthesia and consideration of remimazolam dose in clinical practice.
J Anesth
; 36(4): 493-505, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35708787
3.
Pharmacokinetic properties of remimazolam in subjects with hepatic or renal impairment.
Br J Anaesth
; 127(3): 415-423, 2021 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-34246461
4.
High Throughput Combinatorial Formatting of PcrV Nanobodies for Efficient Potency Improvement.
J Biol Chem
; 291(29): 15243-55, 2016 07 15.
Artigo
Inglês
| MEDLINE | ID: mdl-27226529
5.
Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection.
Antimicrob Agents Chemother
; 60(1): 6-13, 2016 01.
Artigo
Inglês
| MEDLINE | ID: mdl-26438495
6.
Evaluation of efficacy and safety of the anti-VWF Nanobody ALX-0681 in a preclinical baboon model of acquired thrombotic thrombocytopenic purpura.
Blood
; 120(17): 3603-10, 2012 Oct 25.
Artigo
Inglês
| MEDLINE | ID: mdl-22948047
7.
The Metabolism of the New Benzodiazepine Remimazolam.
Curr Drug Metab
; 2024 Mar 21.
Artigo
Inglês
| MEDLINE | ID: mdl-38523539
8.
Synergism of lacosamide with established antiepileptic drugs in the 6-Hz seizure model in mice.
Epilepsia
; 54(7): 1167-75, 2013 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-23750855
9.
Efficacy of remimazolam versus midazolam for procedural sedation: post hoc integrated analyses of three phase 3 clinical trials.
Endosc Int Open
; 10(4): E378-E385, 2022 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-35433203
10.
Impact of concurrent remifentanil on the sedative effects of remimazolam, midazolam and propofol in cynomolgus monkeys.
Eur J Pharmacol
; 890: 173639, 2021 Jan 05.
Artigo
Inglês
| MEDLINE | ID: mdl-33065095
11.
Remimazolam Has Low Oral Bioavailability and No Potential for Misuse in Drug-Facilitated Sexual Assaults, with or Without Alcohol: Results from Two Randomised Clinical Trials.
Drugs R D
; 20(3): 267-277, 2020 Sep.
Artigo
Inglês
| MEDLINE | ID: mdl-32757149
12.
Metabolism of remimazolam in primary human hepatocytes during continuous long-term infusion in a 3-D bioreactor system.
Drug Des Devel Ther
; 13: 1033-1047, 2019.
Artigo
Inglês
| MEDLINE | ID: mdl-31037028
13.
The investigational anticonvulsant lacosamide selectively enhances slow inactivation of voltage-gated sodium channels.
Mol Pharmacol
; 73(1): 157-69, 2008 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-17940193
14.
Pharmacological characterization of a novel investigational antimuscarinic drug, fesoterodine, in vitro and in vivo.
BJU Int
; 101(8): 1036-42, 2008 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-18279452
15.
Lacosamide, the new anticonvulsant, effectively reduces harmaline-induced tremors in rats.
Eur J Pharmacol
; 589(1-3): 114-6, 2008 Jul 28.
Artigo
Inglês
| MEDLINE | ID: mdl-18585381
16.
Delivery of ALX-0171 by inhalation greatly reduces respiratory syncytial virus disease in newborn lambs.
MAbs
; 10(5): 778-795, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29733750
17.
Antihyperalgesic efficacy of lacosamide in a rat model for muscle pain induced by TNF.
Neuropharmacology
; 52(5): 1312-7, 2007 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-17360008
18.
Antinociceptive efficacy of lacosamide in rat models for tumor- and chemotherapy-induced cancer pain.
Eur J Pharmacol
; 565(1-3): 98-104, 2007 Jun 22.
Artigo
Inglês
| MEDLINE | ID: mdl-17395176
19.
Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy.
Epilepsy Res
; 74(2-3): 147-54, 2007 May.
Artigo
Inglês
| MEDLINE | ID: mdl-17433624
20.
Stereoselective effects of the novel anticonvulsant lacosamide against 4-AP induced epileptiform activity in rat visual cortex in vitro.
Neuropharmacology
; 50(1): 98-110, 2006 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-16225894